When I import my sprites into Godot, they look fine in the editor. But when I play the game they start to get distorted and jittery. I scale up the Sprite2D of each node by 8 as I found that was a good size. I also changed texture rendering to Nearest to prevent blurry sprites. Any help would be appreciated.
Actually I think this is because when using pixel art sometimes the pixels don’t line up with the pixels on your screen, causing what you have there. You can try to make your games viewport width and height 640x360 and make the window width and height override any multiple of that. (Make sure embed game on next play is disabled to see what it actually would look like when exported). You can also try using a pixel filtering shader (I think the one I used was SmoothPixelFiltering), which will help out a lot with pixel art on an angle.