How to manipulate scenes on seperate thread

Godot Version

4.2.1

Question

In Godot 3, it was possible in some cases to directly manipulate the scene tree from a separate thread. In Godot 4 direct scene tree manipulation seems to be much more difficult. Does anybody know how? All I am trying to do is adjust the position of a node. It is crucial that this be done on a separate thread. Right now the only way I have been able to do it is by deferring the call, but this is not optimal.