You shouldn’t run into many problems. I’ve made apps. Most of your issues are going to be on the Google Developer Account side anyway, and those suck regardless.
It all runs on Java in the end, so not necessarily. But it will be a lot easier to develop.
Godot is also the best thing I’ve come across for cross-platform development.
I don’t know if that is still a thing for Android exports, but I read (see also the FAQ) it might be worth enabling low-processor mode for non-game applications.