Hi,
According to this thread, making a sprite repeating differently on both axis is not trivial. A thing you could do is using a Polygon2D node that will make the repeating easier, and use a custom shader to adjust the x and y axis yourself.
Something like this:

Here’s the shader in case you want to give it a try:
shader_type canvas_item;
void fragment()
{
vec2 uv = UV;
uv.x = fract(uv.x);
COLOR.rgb = texture(TEXTURE, uv).rgb;
}
Would something like this work for you, or do you absolutely need to use a Sprite2D node?